SNAI1, SNAI2, SNAI3 (AA 188-264) 抗体
(1 reference)Quick Overview for SNAI1, SNAI2, SNAI3 (AA 188-264) 抗体 (ABIN685597)
抗原
适用
宿主
克隆类型
应用范围
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抗原表位
- AA 188-264
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交叉反应
- 人, 兔
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预测反应
- Mouse,Rat
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human Snail
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亚型
- IgG
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应用备注
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WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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: "Epithelial-mesenchymal transition of the eccrine glands is involved in skin fibrosis in morphea." in: The Journal of dermatology, Vol. 40, Issue 9, pp. 720-5, (2013) (PubMed).
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: "Epithelial-mesenchymal transition of the eccrine glands is involved in skin fibrosis in morphea." in: The Journal of dermatology, Vol. 40, Issue 9, pp. 720-5, (2013) (PubMed).
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- SNAI1, SNAI2, SNAI3
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背景
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Synonyms: dJ710H13.1, Protein sna, Protein snail homolog, SLUGH2, SNA, Sna protein, SNAH, SNAI1, Snail homolog 1 Drosophila, Zinc finger protein SNAI1, SNAI1_HUMAN, Protein snail homolog 1, dJ710H13.1, SNAIL, SNAIL1, Protein sna, SLUG, WS2D, SLUGH, SLUGH1, SNAIL2, SMUC, SNAIL3, ZNF293, Zfp293
Background: The zinc finger transcription factor 'SNAIL' was first identified in Drosophila and, along with 'twist', a basic helix-loop-helix transcription factor, is indispensable for mesoderm formation. SNAIL is a repressor of mouse E-cadherin transcription, with expression of SNAIL inversely correlated with expression of E-cadherin. Abnormal expression of SNAIL could underlie the tumorigenic conversion of epithelia associated with loss of E-cadherin expression through screening mouse and human cell lines and by in situ hybridization of primary human tumors undergoing malignant progression.
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分子量
- 29kDa
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基因ID
- 6615, 6591, 333929
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UniProt
- Q02085, P97469, Q9QY31
抗原
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